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A prospective cohort study on the relationship between microplastic exposure, ART outcome and offspring development in infertile women

A prospective cohort study on the relationship between microplastic exposure, ART outcome and offspring development in infertile women

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400091308
Enrollment
Unknown
Registered
2024-10-25
Start date
2024-11-01
Completion date
Unknown
Last updated
2024-10-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

High MPs exposure group:NA
Low MPs exposure group:NA

Sponsors

Women's Hospital School of Medicine Zhejiang University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 38 Years

Inclusion criteria

Inclusion criteria: a. Age: less than 38 years old; b. Women diagnosed with infertility due to tubal factors and receiving in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) for assisted pregnancy; c. Body mass index (BMI) <25kg/m^2; d. No hormone drugs were taken in the 6 months before the test; e. No history of ovarian surgery.

Exclusion criteria

Exclusion criteria: a. Endocrine system diseases b. Immune system diseases c. Uterine malformation d. Polycystic ovary syndrome e. Endometriosis f. Unexplained infertility

Design outcomes

Primary

MeasureTime frame
Follicular fluid microplastic exposure levels;Pregnancy rate;

Secondary

MeasureTime frame
Body mass index;Anti-Müllerian hormone level;Number of eggs retrieved;Fertilization rate;High-quality embryo rate;Miscarriage rate;Live birth rate;Cumulative pregnancy rate;Cumulative abortion rate;Cumulative live birth rate;Gestational age at birth;Sex of offspring;Offspring birth weight;Offspring height;Offspring weight;Offspring head circumference ;Luteinizing hormone level ;Estrogen level;Progesterone level ;Prolactin level;Follicle-stimulating hormone level ;

Countries

China

Contacts

Public ContactHangying Lou

Women's Hospital School of Medicine Zhejiang University

louhangying888@zju.edu.cn+86 137 5814 5377

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026