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A cohort study of ocular function in myopic subjects based on visual pathway radiomics

Ocular function in myopic subjects based on the visual pathway radiomics: a prospective observational cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400091290
Enrollment
Unknown
Registered
2024-10-24
Start date
2024-11-01
Completion date
Unknown
Last updated
2024-10-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myopia

Interventions

High Myopia Group:not available
Moderate and Light Myopia Group:not available

Sponsors

Department of Ophthalmology, Renji Hospital, Shanghai Jiao Tong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Age 6 to 60 years old, regardless of gender; 2. Spherical equivalent refraction: either eye = -0.5D; 3. Distance exophoria =15 prism diopters, distance esophoria =10 prism diopters; 4. With normal thinking and language communication abilities, subjects and their guardians can abide by the relevant rules of the trial, with high compliance; 5. Subjective cooperation and participants or their guardians are able to sign a written informed consent form. A signed, dated informed consent form is required, indicating that the patient (or a legal representative) has been informed of all relevant information about the study.

Exclusion criteria

Exclusion criteria: Subjects who met any of the following criteria were excluded from this study. 1. There are active ocular infections, such as acute conjunctivitis, keratitis, scleritis, uveitis, iridocyclitis, endophthalmitis, etc. 2. Previous surgical history of ocular diseases other than refractive surgery, such as cataract phacoemulsification and intraocular lens implantation, trabeculectomy, vitrectomy, corneal transplantation, etc. 3. Presence of congenital eye diseases, such as congenital cataract, congenital glaucoma, retinopathy of prematurity, familial hereditary retinopathy, etc 4. The presence of progressive eye diseases, such as keratoconus, glaucoma, fundus hemorrhage, diabetic retinopathy, need to be treated with iridectomy, retinal laser photocoagulation, intraocular injection and other treatment interventions; 5. Very low birth weight infant, birth weight less than 1500g. 6. Patients with other systemic diseases that may affect the eyes, such as albinism, epilepsy, and rheumatic immune diseases 7. Patients with severe primary diseases such as liver, kidney, cardiovascular system diseases and mental disorders 8. Other circumstances deemed by the investigator to be inappropriate for trial participation

Design outcomes

Primary

MeasureTime frame
Anterior segment image;fundus image;ocular surface function examination;Refractive state;

Secondary

MeasureTime frame
tear fluid inflammatory cytokines;

Countries

China

Contacts

Public ContactBilian Ke

Renji Hospital, Shanghai Jiao Tong University School of Medicine

kebilian@126.com+86 133 8625 9873

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026