ischemic stroke
Conditions
Interventions
Disease group:None
Healthy Control group:None
Sponsors
Beijing Tiantan Hospital
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: Disease group:1.A definite diagnosis of ischemic stroke; 2.Age =40 years old, gender unlimited; 3.Complete baseline and clinical information;4.Blood samples from which DNA can be extracted;5. Sign informed consent. Healthy control: 1. Age and sex ratio matched the Disease group; 2. Healthy population with baseline information; 3. Blood samples from which DNA can be extracted; 4.Sign informed consent.
Exclusion criteria
Exclusion criteria: Disease group:1.Non-atherosclerotic cerebral infarction, such as cardiogenic cerebral embolism, vasculitis, arterial dissection, MoyaMoya disease, etc. (2) previous serious neurological impairment or mental disorder;2.Complicated with serious systemic diseases, such as heart failure, kidney failure, liver cirrhosis, splenomegalia, interstitial pneumonia, autoimmune diseases, vasculitis, myofibrodysplasia, and blood diseases (leukemia, myeloproliferative diseases or myelodysplastic syndromes, etc.);4.Complicated with intracranial tumors or other malignant tumors;5.Cerebral arteriovenous malformation, cerebral arteriovenous fistula, cerebral artery dissection, cerebral aneurysm and other vascular diseases;6.Myocardial infarction or myocarditis in the last 3 months;7.Have used chemotherapy drugs or been exposed to radiation within the last 3 months;8.pregnancy or breastfeeding, or planning to become pregnant before the end of the study. Healthy control:1.Patients with various types of cerebrovascular diseases in the past, such as cerebral infarction, cerebral hemorrhage, arterial dissection, MoyaMoya disease, etc.; 2.previous serious neurological impairment or mental disorder; 3.Combined with blood system diseases, autoimmune diseases, tumors; 4.Complicated with serious underlying diseases, such as heart failure, kidney failure, cirrhosis, splenomegaly, etc.;5.Myocardial infarction or myocarditis in the last 3 months; 6.Have used chemotherapy drugs or been exposed to radiation within the last 3 months; 7.pregnancy or breastfeeding, or planning to become pregnant before the end of the study.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Clinical score;Clinical manifestations; | — |
Primary
| Measure | Time frame |
|---|---|
| High-risk gene mutation sites; | — |
Countries
China
Contacts
Public Contactjinweina
Beijing Tiantan Hospital
Outcome results
None listed