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Clinical study on the combination of intestinal microbiota transplantation and hormone therapy for non-intestinal acute graft-versus-host disease following haematopoietic stem cell transplantation.

Clinical study on the combination of intestinal microbiota transplantation and hormone therapy for non-intestinal acute graft-versus-host disease following haematopoietic stem cell transplantation.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400091277
Enrollment
Unknown
Registered
2024-10-24
Start date
2024-11-01
Completion date
Unknown
Last updated
2024-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

graft-versus-host disease

Interventions

Sponsors

the First Affiliated Hospital of Ningbo University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Ages 18-80, open to all genders. 2.ECOG scores of 0-3; 3.Expected survival of at least 3 months; 4.Heart, liver, and kidney function: creatinine < 2 times the upper limit of normal (ULN); ALT (alanine aminotransferase) and AST (aspartate aminotransferase) < 2.5 ULN; total bilirubin < 2 ULN; ejection fraction (EF) = 50%. 5.Has sufficient understanding and voluntarily signs the informed consent form.

Exclusion criteria

Exclusion criteria: 1.History of other tumors. 2.Pregnant or breastfeeding women; 3.HIV and HCV infected individuals; patients with uncontrolled HBV virus infection. 4.Combine with patients who have other autoimmune diseases. 5.Patients with poor compliance or mental disorders;

Design outcomes

Primary

MeasureTime frame
Treatment effectiveness rate;

Secondary

MeasureTime frame
OS;PFS;

Countries

China

Contacts

Public ContactPing Zhang; Guifang Ouyang

the First Affiliated Hospital of Ningbo University

lingdujianke@163.com+86 574 87085596

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026