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The exploration of biomarkers in patients with comorbid depression and clinical liver cancer.

The exploration of biomarkers in patients with comorbid depression and clinical liver cancer.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400091257
Enrollment
Unknown
Registered
2024-10-24
Start date
2024-10-24
Completion date
Unknown
Last updated
2024-10-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

liver cancer

Interventions

liver cancer with depression group:None

Sponsors

Institute of Basic Theory for Chinese Medicine, China Academy of Chinese Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: (1) Patients diagnosed with primary hepatocellular carcinoma according to the "Guidelines for the Diagnosis and Treatment of Primary Liver Cancer (2024 Edition)"; (2) Liver cancer staging classified as CNLC Stage Ia, Ib, and IIa, with planned liver resection; (3) Age: 18-50 years; (4) Patients have good compliance and have signed an informed consent form; (5) Able to communicate normally, with no other mental illnesses aside from depression.

Exclusion criteria

Exclusion criteria: (1) Individuals diagnosed by a psychiatrist who must take psychiatric medications; (2) Patients with severe cachexia; (3) Individuals with severe comorbidities such as cardiovascular, cerebrovascular, liver, or kidney diseases; (4) Patients with autoimmune diseases; (5) Pregnant women, women with recent pregnancy intentions, and breastfeeding women; (6) Individuals currently participating in other clinical trials; (7) Patients with liver metastatic cancer or multiple cancers.

Design outcomes

Primary

MeasureTime frame
Liver cancer tissue transcriptome;Liver cancer tissue metabolome;Serum cytokine;

Countries

China

Contacts

Public ContactShen Li

Institute of Basic Theory for Chinese Medicine, China Academy of Chinese Medical Sciences

shenli1116@126.com+86 186 1132 5278

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026