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Study on the therapeutic effect of anti double channel anastomosis on early proximal gastric cancer

Study on the therapeutic effect of anti double channel anastomosis on early proximal gastric cancer

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400091237
Enrollment
Unknown
Registered
2024-10-23
Start date
2025-02-04
Completion date
Unknown
Last updated
2025-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative complications of gastric cancer

Interventions

Experimental group:After resection of the proximal stomach, the jejunum is severed 20cm away from the Qu's ligament, and end-to-end anastomosis is performed 5cm away from the distal end of the jejunum
Control group:After resection of the proximal stomach, the jejunum is severed 20cm away from the Qu's ligament, and end-to-end anastomosis is performed using a stapler at a distance of 5cm from the di

Sponsors

Su Bei People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Voluntarily join this study and sign an informed consent form; 2. Preoperative CT or ultrasound gastroscopy confirmed the lesion as proximal gastric cancer T1 or T2, with no lymph node metastasis. All patients did not receive preoperative radiotherapy, chemotherapy, or other treatments that may affect the outcome. Male or female, age>=18 years old and not exceeding 75 years old; 3. Expected survival period>=3 months; 4. At least one measurable tumor lesion: on spiral CT, the long diameter is greater than or equal to 10 mm, and the short diameter of lymph nodes is greater than or equal to 15 mm; Ordinary CT or physical examination, with a maximum diameter of>=20mm; 5. No major organ failure; 6. No severe coagulation dysfunction; 7. Patients who can tolerate surgery and electronic gastroscopy examination.

Exclusion criteria

Exclusion criteria: 1. Intestinal obstruction; 2. There is extensive adhesion in the peritoneal cavity; 3. There is obvious inflammation in the abdominal cavity; 4. There are high-risk factors for poor anastomotic healing, including anastomotic edema, ischemia, significant tension, severe hypoalbuminemia, etc; 5. Dysfunction of major organs such as the heart, kidneys, liver, and brain; 6. cachexia; 7. Severe coagulation disorders; 8. Individuals with severe or uncontrolled cardiovascular and pulmonary diseases, or those with unstable vital signs due to various reasons; 9. Vulnerable groups, including individuals with mental illness, cognitive impairment, critically ill patients, minors, pregnant women, etc.

Design outcomes

Primary

MeasureTime frame
Whether there are any complications;

Secondary

MeasureTime frame
Survival period;Recovery time of gastrointestinal function;Nutritional indicator;Quality of Life Scale;Operative time;Match time;

Countries

China

Contacts

Public ContactTang Dong

Su Bei People's Hospital

18952783556@yzu.edu.cn+86 189 5278 3556

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026