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The Effect of Liposomal Bupivacaine for Thoracic Paravertebral Block in Video-assisted Thoracoscopic Surgery:A Randomized Controlled Trial

The Effect of Liposomal Bupivacaine for Thoracic Paravertebral Block in Video-assisted Thoracoscopic Surgery:A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400091217
Enrollment
Unknown
Registered
2024-10-23
Start date
2024-10-30
Completion date
Unknown
Last updated
2025-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain relief during thoracoscopic surgery

Interventions

LB group:Prior to the start of the surgery, ultrasound-guided thoracic paravertebral nerve block was performed, and diluted bupivacaine liposomes 100mg (15ml) were administered on both T3 and T5 plane
LP group:Prior to the start of the surgery, ultrasound-guided thoracic paravertebral nerve block was performed, and 15ml of 0.3% ropivacaine was administered to both T3 and T5 planes

Sponsors

Qingdao University Affiliated Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1) Age range: 18-65 years old 2) BMI18-30kg/? 3) ASA I-III levels 4) Patients planning to undergo thoracoscopic surgery 5) Voluntary signing of informed consent form

Exclusion criteria

Exclusion criteria: 1) Patients with contraindications for regional blockade 2) Individuals who are allergic to or have absolute contraindications to the drugs used in the study 3) Patients with severe cardiovascular and cerebrovascular diseases, liver dysfunction, and arrhythmia 4) Patients with a history of taking chronic analgesics 5) Patients with communication barriers 6) Pregnant women

Design outcomes

Primary

MeasureTime frame
Total consumption of opioid drugs within 72 hours after surgery;Maximum NRS score 24 hours after surgery;Maximum NRS score 48 hours after surgery;Maximum NRS score 72 hours after surgery;Recovery time of postoperative gastrointestinal function;Postoperative pain relief frequency;

Secondary

MeasureTime frame
Maximum NRS score 6 hours after surgery;Maximum NRS score 12 hours after surgery;

Countries

China

Contacts

Public ContactWei Feng

Qingdao University Affiliated Hospital

fengwei123@163.com+86 186 6180 5500

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026