Comparison of the clinical efficacy of laparoscopic excision versus hysteroscopic resection in the treatment of cesarean scar pregnancy: A multicenter, randomized, controlled clinical trial

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400091216

Enrollment

Unknown

Registered

2024-10-23

Start date

2024-11-01

Completion date

Unknown

Last updated

2024-10-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cesarean scar pregnancy

Interventions

hysteroscopic resection group:hysteroscopic resection

laparoscopic excision group:laparoscopic excision

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. According to the criteria for practical clinical classification of caesarean section scar pregnancy (Qilu classification), patients with type IIB and IIIA CSP were diagnosed (the thinnest remaining muscle layer =3mm, 3cm< average diameter of pregnancy sac or mass =5cm, without uterine arteriovenous malformations); 2. Primary treated CSP patients over 18 years old and under 45 years old; 3. Patients who voluntarily choose surgical treatment; 4. Patients can cooperate to complete postoperative follow-up; 5. Only one previous history of cesarean section operation; 6. Single pregnancy; 7. Duration of menopause =12 weeks; 8. The subject (or his legal representative) understands the nature of the study and signs the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients who have received pre-treatment such as drug therapy, uterine artery embolization, and uterine clearance surgery; 2. Ectopic pregnancy in other parts and gestational trophoblastic disease 3. Previous history of uterine or pelvic surgery; 4. Patients with past or current malignant tumors; 5. History of major organ transplantation and immune disease; 6. Hemodynamic instability, severe coagulopathy, severe internal and surgical complications, anesthesia contraindication and inability to tolerate surgery; 7. Unable or unwilling to sign informed consent or comply with study requirements.

Design outcomes

Primary

Measure	Time frame
Initial surgical success rate;	—

Secondary

Measure	Time frame
intraoperative bloood loss;operation time;intraoperative immediate complications;hospital stay;Postoperative uterine involution;Postoperative menstruation recovery;Postoperative complications;future pregnancy rate;Repetitive uterine scar pregnancy rate;	—

Countries

China

Contacts

Public ContactBaoxia Cui

Qilu Hospital of Shandong University

cuibaoxia@sdu.edu.cn+86 185 6008 1862

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026