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Study on the related factors of perioperative cognitive function changes in patients with metabolic syndrome

Study on the related factors of perioperative cognitive function changes in patients with metabolic syndrome

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400091182
Enrollment
Unknown
Registered
2024-10-22
Start date
2024-10-23
Completion date
Unknown
Last updated
2024-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metabolic syndrome

Interventions

(Retrospective study) Delayed extubation group:NA
(Retrospective study) Non delayed extubation group:NA
(Prospective study) Delirium group :This is an observational study with no intervention
(Prospective study) Non-delirium group :This is an observational study with no intervention

Sponsors

Affiliated hospital of Zunyi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1 Inclusion criteria for retrospective studies: ? Surgical patients aged 18-75 years old; ? After the surgery, enter PACU to revive the patient; ? The anesthesia method is general anesthesia with tracheal intubation only ? Complete clinical data. 2 Inclusion criteria for prospective studies ? Surgical patients aged 18-75 years old; ? Patients with the main complaint of ‘weight gain’ who want to undergo bariatric surgery in the Gastrointestinal Surgery Department of the Affiliated Hospital of Zunyi Medical University ? Complete clinical data ? Normal thinking and cognitive ability ? Consciousness and ability to complete the questionnaires independently after the operation; ? Knowledge of the content of our study and voluntary participants;

Exclusion criteria

Exclusion criteria: 1 Exclusion criteria for retrospective studies: ? Patients with incomplete clinical data; ? The anesthesia method is general anesthesia without tracheal intubation; ? Patients who did not enter PACU for resuscitation after surgery 2 Exclusion criteria for prospective studies: ? Patients refused to participate in the study ? Age 65 years. ? Combined asthma, central system diseases and chronic obstructive pulmonary disease; ? Those with previous mental illness or psychological disorder; ? Those who underwent oral and maxillofacial surgery; ? Those with incomplete clinical information and unable to be followed up.

Design outcomes

Primary

MeasureTime frame
(Retrospective study) Risk factors for delayed extubation;(Prospective study) Occurrence of delirium;(Prospective Study)Blood transcriptomics;

Secondary

MeasureTime frame
(Prospective Study) Blood Metabolomics;(Prospective Study)Blood proteomics;

Countries

China

Contacts

Public ContactMengyuan Deng,Zhaoqiong Zhu

Department of Anaesthesiology, Affiliated Hospital of Zunyi Medical University

395368688@qq.com+86 159 8508 0812

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026