Fine lines or wrinkles
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) The inclusion criteria are women aged 30 to 60 years old; (2) The corners of the eyes on both sides have fine lines or wrinkles, in line with the ‘Skin Aging Atlas’ grading atlas of the corners of the eyes wrinkles grade 1 ~ 6, or in line with the ‘Evaluation Guidelines for Anti-Wrinkle Products to Obtain the Effectiveness of the New Regulations’ grading atlas of the corners of the corners of the eyes wrinkles grades 1 ~ 7, and the left and right corners of the corners of the eyes wrinkles grade is the same; (3) People who are in good health, with no obvious brain, heart, liver, lung, kidney, or blood disorders, no history of long-term medication, and who volunteer to be tested to ensure cooperation; (4) Can read Chinese and accurately understand the trial process, voluntarily participate in the trial and sign the informed consent form for the trial study; (5) Do not use any other drugs and health products that will have an effect on the results during the trial; (6) Those who are able to co-operate and participate in the return visit time of the trial study, and promptly reflect any changes in their own health status or medication, symptoms of adverse reactions, and are able to comply with the requirements of the study as well as the time schedule.
Exclusion criteria
Exclusion criteria: (1) Those who are currently pregnant or breastfeeding; (2) Those who are allergic to bird's nest, and those who have other previous history of food allergy; (3) Patients with combination of serious diseases such as cardiac, hepatic, renal and haematopoietic systems or acute exacerbation of chronic diseases; (4) Patients with diseases that may affect the metabolism of the test drug; (5) Patients with infectious diseases or immunodeficiency diseases; (6) Those who have taken items related to the function of the test for a short period of time, which affects the judgement of the results; (7) Patients with poor lifestyle habits, such as alcoholism, smoking, drug abuse, etc., which may affect the results of the test; (8) Others who are deemed unsuitable to participate in the trial by clinical assessment; (9) Those who are unable to understand the requirements of the trial, sign the informed consent or complete the trial process.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| water content of stratum corneum;skin gloss;melanin content;skin conditions in the corner of the eye; | — |
Secondary
| Measure | Time frame |
|---|---|
| transdermal water loss; | — |
Countries
China
Contacts
Xianyang Hospital, Yan'an University