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To investigate the effect of remimazolam on postoperative sleep quality in patients undergoing general anesthesia

To investigate the effect of remimazolam on postoperative sleep quality in patients undergoing general anesthesia

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400091162
Enrollment
Unknown
Registered
2024-10-22
Start date
2024-11-01
Completion date
Unknown
Last updated
2024-10-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gallstone

Interventions

Group of Remimazolam:Anesthesia was induced with 0.15-0.25 mg/kg of remimazolam, anesthesia was maintained with 0.2-1.0 mg/kg ·h of remimazolam.
Propofol group:Anesthesia induction uses propofol 1.5-2.5mg/kg, and anesthesia maintenance uses propofol target controlled infusion 4-12 mg/kg · h

Sponsors

Shapingba hospital affiliated to Chongqing University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients and their families signed informed consent for elective laparoscopic cholecystectomy. Age 20-60 yr, body mass index 18.5-26.0 kg /m2, American Society of Anesthesiologists physical status ? or ?.

Exclusion criteria

Exclusion criteria: 1. Preoperative language communication and cognitive impairment; 2. Preoperative sleep disorders (PSQI>7); 3. History of severe mental or neurological disease; 4, drug or psychotropic drug abuse, long-term use of steroid drugs, hormone drugs; 5. Severe visual and hearing impairment.

Design outcomes

Primary

MeasureTime frame
Pittsburgh sleep disturbance index (PSQI) ;Related sleep indicators collected by Huawei Bracelet;

Secondary

MeasureTime frame
Consumption of two groups of anesthetic and vasoactive drugs during the perioperative period;Postoperative NRS score and number of controlled compressions of analgesic pump;The incidence of adverse reactions;

Countries

China

Contacts

Public ContactBaizhou Chen

Shapingba hospital affiliated to Chongqing University

437069051@qq.com+86 176 2388 3648

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026