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Effect of Liposomal Bupivacaine Wound Infiltration on Chronic Pain after Thoracoscopic Lung Surgery: A Randomized Controlled Trial

Effect of Liposomal Bupivacaine Wound Infiltration on Chronic Pain after Thoracoscopic Lung Surgery: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400091157
Enrollment
Unknown
Registered
2024-10-22
Start date
2024-10-23
Completion date
Unknown
Last updated
2024-10-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative chronic pain

Interventions

Liposomal Bupivacaine:Before the end of surgery, patients will receive liposomal bupivacaine (266mg, 20ml) for wound infiltration
Ropivacaine group (Rop group):Before the end of surgery, patients will receive 0.375% ropivacaine saline (20 ml) for wound infiltration

Sponsors

The First Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1) Age =18 years old, male or female sex; 2) American society of Anesthesiologists (ASA) physical status I-III; 3) Undergoing elective unilateral thoracoscopic lung surgery; 4) Clear understanding the research process and providing written informed consent.

Exclusion criteria

Exclusion criteria: 1) Allergy to bupivacaine, ropivacaine or other anesthetics; 2) Previous history of thoracic surgery; 3) History of neuropathic or chronic pain (defined as pain that has persisted for >3 months) or long-term use of analgesics before surgery (defined as use for >3 months); 4) Inability to understand the study protocol, or refusal to participate in the study.

Design outcomes

Primary

MeasureTime frame
Incidence of postoperative chronic pain ;

Secondary

MeasureTime frame
Incisional pain scores;Postoperative analgesic consumption;Quality of recovery score;Incidence of postoperative pain ;

Countries

China

Contacts

Public ContactPeng Ke

Department of Anesthesiology, The First Affiliated Hospital of Soochow University

pengke@suda.edu.cn+86 159 6215 5989

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026