hyperalgesia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Participants should be between the ages of 18 and 30; (2) Reporting chronic stress experiences, such as long-term academic pressure, family issues, or other personal problems; Participants should self-report experiencing persistent or recurrent pain in the past 6 months that they believe is related to their stress. Psychological assessments should indicate stress-related psychological reactions, such as elevated perceived stress levels; (3) Healthy individuals with normal physical examination findings and good overall health status who are able to participate in all study procedures; (4) Willingness to participate in the study and ability to provide informed consent.
Exclusion criteria
Exclusion criteria: (1) History of major chronic diseases such as cardiovascular disease, diabetes, or long-term use of immunosuppressants, hormonal drugs, or other medications that may affect pain perception or stress response; (2) History of severe mental illness, such as schizophrenia, major depressive disorder, or currently undergoing psychotherapy; (3) Presence of neurological disorders that could interfere with pain assessment or data interpretation; (4) Physical or psychological conditions that make the participant unsuitable for participation in questionnaires or clinical assessments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain sensitivity;Glucocorticoid Levels;Inflammatory markers;Leukocyte subsets; | — |
Secondary
| Measure | Time frame |
|---|---|
| Chronic stress;Non-suicidal self-injury (NSSI); | — |
Countries
China
Contacts
Department of Psychology, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China