Head and neck squamous cell carcinoma
Conditions
Interventions
Group of patients with head and neck squamous cell carcinoma:None
Sponsors
Oral and Maxillofacial Surgery, Cangzhou central hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Pathological diagnosis (surgical pathological section or needle biopsy) for HNSCC; 2. The stage is stage IV (according to the 8th edition of the AJCC Cancer Staging Manual); 3. The clinical stage is stage I, II or III, local recurrence or distant metastasis after radical resection; 4. Presence of evaluable lesions on imaging; 5. ECOG score of 0-1 points; 6. Have not received chemoradiotherapy in the past, or have stopped treatment for at least 6 months; 7. Have complete clinical records and follow-up data
Exclusion criteria
Exclusion criteria: 1. Patients who have received immunotherapy such as CTLA-4 inhibitors and PD-1 inhibitors in the past; 2. ECOG > 2 points, expected survival time less than 3 months; 3. Recent systemic active infection or acute exacerbation of chronic diseases, unable to tolerate chemotherapy; 4. Previous autoimmune diseases and hematologic diseases; 5. Previous or concurrent malignant tumors or serious and uncontrollable diseases other than HNSCC.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival;Progression-free survival ; | — |
Countries
China
Contacts
Public ContactQi Mengchun
Oral and Maxillofacial Surgery, Cangzhou central hospital
Outcome results
None listed