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Preclinical study and application of fertility preservation in patients with gynecologic malignancies (Full-cycle management of fertility and life after fertility preserving treatment in patients with endometrial cancer) - The effect of a positive thought-based psychological intervention on in vitro fertilization-embryo transfer pregnancy outcomes

Effects of a positive thought-based psychological intervention on pregnancy outcome in in vitro fertilization-embryo transfer

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400091094
Enrollment
Unknown
Registered
2024-10-21
Start date
2025-06-05
Completion date
Unknown
Last updated
2026-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female infertility

Interventions

Experimental group:Subjects received a 2-day ground-based course on mindfulness-based maternal mind-body intervention techniques and a 30-day web-based card, which consisted of course content on mindf
Control group:During the same period of time, a 30-day web-based card is conducted, and the web-based card study is a health education course related to assisted reproductive technology.

Sponsors

Beijing Chaoyang Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Mentally competent, with the ability to read, write, and understand Chinese, and who has provided informed consent to participate in this study. 2. Aged 20–40 years; 3. Undergoing the first to third cycle of IVF-ET treatment; 4. No history of childbirth;

Exclusion criteria

Exclusion criteria: 1. Chromosomal abnormalities in either partner; 2. BMI >= 30 kg/m^2; 3. History of uterine malformations, intrauterine adhesions, or untreated submucosal fibroids/adenomyosis; 4. Untreated hydrosalpinx visible on ultrasound; 5. History of recurrent miscarriage or thrombophilia risk factors; 6. Patients with premature ovarian failure (POF) or premature ovarian insufficiency (POI); 7. Contraindications for assisted reproductive technology (ART) or pregnancy, such as a history of breast cancer; 8. Clinically diagnosed anxiety or depressive disorders, or history of treatment for psychological/psychiatric conditions; 9. Recent meditation experience (participation in any form of eight-week mindfulness training or short-term intensive mindfulness training, including but not limited to MBSR, MBCT, etc.). 6. History of recurrent miscarriage; 7. Patients with premature ovarian failure (POF) or premature ovarian insufficiency (POI), contraindications for assisted reproductive technology or pregnancy, such as history of breast cancer or thrombosis risk. 8. Diagnosed anxiety disorder or history of psychological/psychiatric treatment. 9. Recent meditation experience (participation in any form of eight-week mindfulness training or short-term intensive mindfulness training, including but not limited to MBSR, MBCT, etc.). 10. Currently taking medications affecting cortisol levels. 11. Pregnant women, postpartum individuals, or their family members unwilling to cooperate.

Design outcomes

Primary

MeasureTime frame
Psychological stress and sleep improvement status;

Secondary

MeasureTime frame
The concentration of cortisol in saliva;EEG brainwave signal characteristic changes;Ovulation induction effect;Pregnancy outcome;

Countries

China

Contacts

Public ContactQun Lu

Beijing Chaoyang Hospital, Capital Medical University

luqun1023@sina.com+86 10 8523 1435

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 20, 2026