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A study on the efficacy of TACE-HAIC combined targeting and immunotherapy for hepatocellular carcinoma with portal vein tumor thrombus

A study on the efficacy of TACE-HAIC combined targeting and immunotherapy for hepatocellular carcinoma with portal vein tumor thrombus

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400091091
Enrollment
Unknown
Registered
2024-10-21
Start date
2024-10-21
Completion date
Unknown
Last updated
2024-10-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular carcinoma

Interventions

Group 1 (TACE+HAIC+Lenvatinib+ Camrelizumab0:NA
Group 2 (TACE+Lenvatinib+ Camrelizumab):NA
Group 3 (HAIC+Lenvatinib+ Camrelizumab):NA
Group 4 (TACE alone):NA

Sponsors

Harbin Medical University Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with primary HCC with PVTT (Vp1-4) who received initial treatment with TACE or combination therapy including TACE-HAIC and a tyrosine kinase inhibitor or PD-1 inhibitor; 2. Aged between 18 and 75 years old; 3. Child-Pugh: A or B; 4. ECOG =1;

Exclusion criteria

Exclusion criteria: 1. Serious heart, lung or kidney disease; 2. A previous diagnosis of a different primary cancer; 3. Incomplete medical records; 4. Patients who cannot be followed up;

Design outcomes

Primary

MeasureTime frame
Overall survival;

Secondary

MeasureTime frame
Objective response rate;Progression-free survival;Incidence of adverse reactions;

Countries

China

Contacts

Public ContactLiu Ruibao

Harbin Medical University Cancer Hospital

liu_ruibao@sina.com+86 137 9605 6596

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026