Cognitive function in healthy elderly people and elderly people with mild cognitive impairment
Conditions
Interventions
Healthy treatment group:The subjects received DCES cognitive training 3-5 times a week, each time for 30 minutes, for 10 consecutive weeks, with a cumulative total of 30-50 sessions
Healthy control group:Subjects do not accept human intervention with cognitive load
Mild cognitive impairment treatment group:The subjects received DCES cognitive training 3-5 times a week, each time for 30 minutes, for 10 consecutive weeks, with a cumulative total of 30-50 sessions
Mild cognitive impairment control group:Subjects do not accept human intervention with cognitive load
Sponsors
Beijing Huilongguan Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: Healthy elder adults: 1. Patients/their families have no recognition disorders, and there is no other diseases with DSM-V shaft i; 2. 60 = age = 85 years old, the education period of education = 5 years; 3. After evaluation of clinical dementia assessment tables CDR = 0, MOCA = 26 points, normal daily life ability (ADL <18 points); 4. ischemic index quantity table (HIS) =4 points; 5. No obvious vision and hearing impairment; 6. The elderly depression table (GDS) =10 points or there is no history of depression in the past two years; 7. MRI (MRI) to check the history of cerebral -free disease; 8. voluntarily participate in clinical research and signed an informed letter; Mild cognitive impairment: 1. The patient/family member has a chief complaint of cognitive impairment, and it has been confirmed that their cognitive function has decreased compared to before in the past year, with age ranging from 60 to 85 years old; 2. Primary school education or above; 3. After evaluation, the Clinical Dementia Rating Scale CDR=0.5, with a score of 18<MoCA = 25 points; 4. Daily living ability scale (ADL) (14 items)<18 points; 5. Ischemia Scale (HIS) = 4 points; 6. Elderly Depression Scale (GDS) = 10 points or no history of depression in the past two years; 7. No obvious visual or hearing impairment; 8. Brain magnetic resonance imaging (MRI) without a history of organic brain diseases; 9. Voluntarily participate in clinical research and sign a letter of understanding;
Exclusion criteria
Exclusion criteria: Common exclusion criteria: 1. History of cerebral infarction, cerebral hemorrhage, traumatic brain injury, neurodegenerative diseases, and other organic brain diseases; 2. Severe physical diseases such as heart failure, emphysema, liver and kidney dysfunction; 3. History of mental illnesses such as depression, anxiety, substance abuse, and schizophrenia; 4. Taking cholinesterase inhibitors or other puzzle drugs; 5. Individuals with auditory/visual perceptual impairments who are unable to maintain a fixed gaze on the training device screen for at least 30 minutes; 6. Unable to persist in participating in DCES treatment; 7. Researchers believe that patients may have other circumstances that prevent them from participating in DCES treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rBANS total score;ISI score; | — |
Secondary
| Measure | Time frame |
|---|---|
| MoCA total score;rBANs Factor score; | — |
Countries
China
Contacts
Public ContactFude Yang
Beijing Huilongguan Hospital
Outcome results
None listed