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AKI CRRT RCT A multicenter RCT study on the timing of CRRT cessation in severe AKI patients based on diuretic stress test

AKI CRRT RCT A multicenter RCT study on the timing of CRRT cessation in severe AKI patients based on diuretic stress test

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400091040
Enrollment
Unknown
Registered
2024-10-19
Start date
2022-06-18
Completion date
Unknown
Last updated
2024-10-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute kidney injury

Interventions

experimental group:Furosemide load test:Patients who had used furosemide within one week before CRRT discontinuation were given 1.5mg/kg of furosemide during CRRT withdrawal to observe whether the uri
If furosemide has not been used in the week before CRRT shutdown, 1 mg/kg of furosemide is given intravenously.
control group:none

Sponsors

Zhejiang Provincial People's Hospital(Affiliated People's Hospital, Hangzhou Medical College)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients admitted to the ICU, APACHE II score>8 points 2. Patients with severe acute kidney injury undergoing CRRT treatment 3. Age>18 years old

Exclusion criteria

Exclusion criteria: 1. Near death or severe shock resuscitation failure 2. Patients with severe liver dysfunction or terminal stage malignant tumors 3. GCS score of 3 points for severe cerebrovascular disease or traumatic brain injury patients 4. Patients with end-stage renal disease who need long-term maintenance dialysis 5. Received RRT treatment before admitted the ICU this time

Design outcomes

Primary

MeasureTime frame
Weaning success rate;

Secondary

MeasureTime frame
Retreatment of RRT within 28 days;Renal function recovery;

Countries

China

Contacts

Public ContactYang Xianghong

Emergency and Critical Care Center, Intensive Care Unit, Zhejiang Provincial People's Hospital(Affiliated People's Hospital, Hangzhou Medical College),Hangzhou, Zhejiang, China 310014.

jyy623@163.com+86 138 5802 0036

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 10, 2026