spinal anaesthesia-induced hypotension during cesarean section
Conditions
Interventions
Group Phenylephrine (Group PE) :Intravenous pump norepinephrine
Group Metaraminol (Group ME):Intravenous pump metaraminol
Sponsors
Wenling Maternal and Child Health Care Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: ASA I-II, women with singleton pregnancy (gestational age >= 37 weeks) undergoing elective cesarean section.
Exclusion criteria
Exclusion criteria: ASA=?,SBP 140mmHg, height 170 cm, age 40 years, obesity (body mass index =35kg/ m^2), allergy to phenylephrine or metaraminol , gestational hypertension, diabetes mellitus, cardiovascular disease, coagulation disorders, thrombocytopenia, intraspinal anesthesia contraindications, placenta previa, rupture of fetal membrane, fetal congenital malformations, etc
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Umbilical artery blood pH;Maternal hemodynamics parameters (hypertension and heart rate) within 15 minutes after spinal anesthesia;Total consumption of vasoactive drugs before delivery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood gas analysis of other fetal umbilical arteries and umbilical veins;Apgar score 1 and 5 minutes after delivery;Incidence of maternal hypotension from lumbar anesthesia to fetal delivery;Time of first occurrence of hypotension after lumbar anesthesia;The incidence of severe maternal hypotension, reactive hypertension, bradycardia, nausea and vomiting; | — |
Countries
China
Contacts
Public ContactZhimin Sheng
Wenling Maternal and Child Health Care Hospital
Outcome results
None listed