chronic hepatitis B and hepatitis B cirrhosis
Conditions
Interventions
Sponsors
Chinese People's Liberation Army Rocket Force Characteristic Medical Center
Eligibility
Sex/Gender
All
Age
26 Years to 84 Years
Inclusion criteria
Inclusion criteria: Chronic Hepatitis B and Hepatitis B Cirrhosis Group : ? Meets the diagnostic criteria of the "Guidelines for the Prevention and Treatment of Chronic Hepatitis B (2022 Edition)"; ? Has been infected with hepatitis B virus for more than six months; ? Signed an informed consent form, voluntarily participating in the study. Healthy Group: ? Individuals confirmed to be within the range of physical health through a health examination; ? Those who have signed an informed consent form and voluntarily participate in the study.
Exclusion criteria
Exclusion criteria: Chronic Hepatitis B and Hepatitis B Cirrhosis Group : ? Patients infected within 3 months; ? Received antibiotics within 3 months; ? Received probiotics and probiotics within 3 months; ? Co-infection with hepatitis C virus, hepatitis D virus, human immunodeficiency virus and other hepatitis; ? Concomitant hypertension, diabetes, obesity, obvious atherosclerosis, chronic kidney disease, history of gastrointestinal surgery, inflammatory bowel disease, irritable bowel syndrome, malignant tumors, autoimmune diseases, Parkinson’s disease, Alzheimer’s disease, and stroke; ?Mental illness; ? Pregnant or lactating women. Healthy Group: ? Those who do not pass the health examination; ? Patients infected within the past 3 months; ? Individuals who have received antibiotic treatment within the past 3 months; ? Individuals who have undergone probiotic therapy within the past 3 months; ? Those who have experienced diarrhea in the recent 3 months; ? Mental illness; ? Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gut microbiota; | — |
Secondary
| Measure | Time frame |
|---|---|
| Complete blood count;liver function ;renal function;blood ammonia;four liver fibrosis markers;five hepatitis B markers;hepatitis B DNA quantification;infection indicators;Basic information; | — |
Countries
China
Contacts
Public ContactChangzheng Li
Chinese People's Liberation Army Rocket Force Characteristic Medical Center
Outcome results
None listed