Sudden pain after knee replacement surgery
Conditions
Interventions
Experimental group Z:Ultrasound guided adductor block: 133mg of bupivacaine liposomes were diluted to 20ml with physiological saline.
Control group C:Ultrasound guided adductor block: 0.375% bupivacaine 20 ml.
Sponsors
Bazhong Central Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 79 Years
Inclusion criteria
Inclusion criteria: The age range of the patients at Bazhong Central Hospital is 50-79 years old, with American Society of Anesthesiologists (ASA) grades I-III. They are scheduled to undergo elective knee replacement surgery under general anesthesia.
Exclusion criteria
Exclusion criteria: 1. Contraindications for peripheral nerve block (such as infection at the puncture site, sepsis, coagulation dysfunction, and allergy to local anesthetics); 2. There is already central or peripheral neuropathy in the lower limbs before surgery; 3. Individuals with cognitive function, hearing, language disorders, a history of mental illness, difficulty communicating, or severe mental disorders that make it difficult to cooperate; 4. Long term use of analgesic drugs; ? Serious cardiovascular or pulmonary diseases; 6. BMI>30kg/m^2.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of Rebound Pain within 24 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of Rebound Pain within 12 hours after surgery;Improved Rebound Pain Score;Score on the Numerical Rating Scale during Rest and Exercise;The time to enter the first pain cycle within 24 hours after surgery;Within 2 hours after surgery until the first onset of Rebound Pain;Accumulated opioid usage;Adverse reactions: poisoning, allergy, urinary retention, etc;Pittsburgh Sleep Quality Index scores before surgery, on the day of surgery, on the first day after surgery, and on the second day after surgery;Hospital stay;Patient satisfaction; | — |
Countries
China
Contacts
Public ContactWenming Qin
Bazhong Central Hospital
Outcome results
None listed