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The characteristics of brain function in patients with post-stroke dysphagia based on fNIRS and its correlation with clinical swallowing scales

The characteristics of brain function in patients with post-stroke dysphagia based on fNIRS and its correlation with clinical swallowing scales

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400090952
Enrollment
Unknown
Registered
2024-10-16
Start date
2024-11-01
Completion date
Unknown
Last updated
2024-10-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

NPSD group:none
Healthy control group:none

Sponsors

Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1.patient with a stroke ? Age between 30 and 85 years old. ? Stroke was confirmed by CT or MRI scan during hospitalization in Sir Run Run Shaw Hospital, Zhejiang University School of Medicine. ? first onset of unilateral stroke, the course of disease =6 months; ? There were different degrees of dysphagia, and the Kubota drinking test was 2-5. ? The vital signs were stable, there was no obvious abnormality in listening and comprehension, the cognitive ability was good, and the MMSE score was =21. ? voluntarily participate in this study and sign the informed consent. If the subjects were unable to read and sign the informed consent form due to incapacity or other reasons, their guardians were required to act for them during the informed consent process and sign the informed consent form. If the subjects were unable to read the informed consent form (e.g., illiterate subjects), witnesses were required to witness the informed consent process and sign the informed consent. 2.Healthy subjects ? Age between 30 and 85 years old. ? no previous history of stroke, brain tumor, brain trauma or mental illness. ? No swallowing dysfunction, Eating assessment questionnaire-10 (EAT-10) score < 3. ? voluntarily participated in this study and signed the informed consent. If the subjects were unable to read and sign the informed consent form due to incapacity or other reasons, their guardians were required to act for them during the informed consent process and sign the informed consent form. If the subjects were unable to read the informed consent form (e.g., illiterate subjects), witnesses were required to witness the informed consent process and sign the informed consent.

Exclusion criteria

Exclusion criteria: ? Dysphagia caused by non-cerebrovascular accident, such as motor neuron disease, head and neck tumor surgery, muscle disease, etc. ? Important organ failure, or critical condition requiring rescue; Combined with untreated malignant tumors or major primary diseases of the respiratory system, cardiovascular system, liver, kidney, hematopoietic system, etc. ? after decompressive craniectomy or other skull defects. (4) vulnerable groups, including people with mental illness, critically ill patients, people with visual and hearing impairment, and pregnant women. ? other situations that cannot cooperate with the completion of the test.

Design outcomes

Primary

MeasureTime frame
Blood oxygen concentration in the cerebral cortex;

Countries

China

Contacts

Public Contactzhang lu

Sir Run Run Shaw Hospital, Zhejiang University School of Medicine Sir Run Run Shaw Hospital, Zhejiang University School of Medicine

anxiaokui733@163.com+86 136 7583 6899

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026