prenatal perfluoroalkyl substances (PFAS) exposure
Conditions
Interventions
Observation group:None
Sponsors
Nantong Maternal and Child Health Care Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 35 Years
Inclusion criteria
Inclusion criteria: (1) Maternal aged between 20 and 35 (20 years old is the legal marriage age, and 35 years old or older is considered elderly parturient woman); (2) singleton mothers who have been registered in our hospital, have regular obstetric checkups, complete clinical data, and have had natural deliveries; (3) deliver full-term newborn babies (37+0-41+6 weeks); (4) have normal comprehension ability and can clearly answer questions.
Exclusion criteria
Exclusion criteria: (1) Pregnancy having used assisted reproductive technology; (2) Parturient women who had diabetes, thyroid diseases, hypertension and other diseases affecting the neurobehavioral development of offspring before pregnancy and during this pregnancy. (3) Those who are unwilling to cooperate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PFAS in maternal blood;Inflammatory factors in maternal blood;Inflammatory factors in Cord blood;Inflammatory factors in placental tissue;Neonatal behavioral neurological assessment;Infant neurobehavioral development;Maternal PFAS exposure-related dietary behaviors in late pregnancy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Physical development of newborn;Infant physical development; | — |
Countries
China
Contacts
Public ContactAnan Zhang/Zhifang Chen
Nantong Maternal and Child Health Care Hospital
Outcome results
None listed