General anesthesia induction in elderly patients
Conditions
Interventions
Sufentanil + ciprofol group:Sufentanil was administered at 0.1 µg/kg, followed five minutes later by the initial dose of ciprofol (0.3 mg/kg). The subsequent dose of the latter patient was increased
ciprofol group:5 ml of normal saline was given first, and the initial dose of ciprofol (0.3 mg/kg) was given five minutes later. The subsequent dose of the latter patient was increased or decreased b
Sponsors
Hangzhou Linping District first People's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: ? 65-85 years old; ? Surgery under general anesthesia is required; ?ASA (American Society of Anesthesiologists) Levels I-III; ? Body mass index (BMI) between 18-25 kg/m^2;
Exclusion criteria
Exclusion criteria: ? Allergic to cyclopofol or contraindicated to the use of cyclopofol (soybean allergy) Preoperative disturbance of consciousness or chronic pain Long-term use of analgesics, psychotropic drugs (including opioids, NSAIDs, sedatives, antidepressants) ? The patient is expected to have a difficult airway or a history of abnormal anesthesia (4) Patients with tumors and serious cardiovascular and cerebrovascular diseases 5. Use of sedatives, antiemetic, antipruritic drugs 24 hours before surgery, or use of monoamine oxidase inhibitors or antidepressants within 15 days ? Researchers who do not agree to participate in or are participating in other drug trials
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eeg bispectral index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood Pressure;HeartRate;Saturation of Pulse Oxygenation;Injection pain;hypotension;bradycardia;myofibrillation;Postoperative nausea and vomiting;Respiratory depression;Low oxygen sats; | — |
Countries
china
Contacts
Public ContactQing Han
Hangzhou Linping District first People's Hospital
Outcome results
None listed