Bowel preparation protocol before colonoscopy
Conditions
Interventions
experimental group:1L Polyethylene Glycol (PEG) + Lubiprostone
control group:2L Polyethylene Glycol (PEG)
Sponsors
The First Affiliated Hospital Of Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Age = 18 years; (2) Patients scheduled for colonoscopy; (3)signed the informed consent
Exclusion criteria
Exclusion criteria: (1) age >65 years; (2) constipation; (3) body mass index (BMI) greater than 25 kg/m2; (4) previous gastrectomy or colorectal resection; (5) history of Parkinson's disease, stroke, or spinal cord injury; (6) use of tricyclic antidepressant or narcotic medications; (7) severe heart or lung disease (American Society of Anesthesiologists Physical Status 3 or 4); (8 ) severe renal failure (creatinine clearance <30mL/min); (9) decompensated cirrhosis of the liver or severe systemic disease; (10) impaired gag reflex or impaired mental status; (11) pregnant or breastfeeding; (12) allergy to PEG or LB; and (13) absence of informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the quality of bowel preparation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cecal Intubation Rate;Cecal intubation time;advancing time;withdrawal time;Adenoma detection rate;acceptability;compliance; | — |
Countries
China
Contacts
Public ContactLiang Peng
The First Affiliated Hospital Of Guangzhou Medical University
Outcome results
None listed