Polycystic ovary syndrome
Conditions
Interventions
The group of Empagliflozin:Empagliflozin
The group of Metformin:Metformin
Sponsors
The Second Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: ? Age:18-40 years old; ? BMI:24.0-38.0 kg/m2; ? Not combined with other serious chronic diseases; ? Normal liver function, renal function and electrocardiogram examination; ? Meeting the diagnostic criteria of polycystic ovary syndrome and excludes other diseases such as congenital adrenal cortical hyperplasia, Cushing's syndrome, and androgen secreting tumors. ? Fully understanding the trial content, voluntarily participate in the trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: ? With diabetes (type 1 or type 2) ? With chronic diseases of heart, liver, or kidney; Individuals with drug allergy, allergic diseases or allergic constitution; Smokers and alcoholics; ? Concomitant Cushing's syndrome, congenital adrenal hyperplasia, benign and malignant tumors of various systems, liver and kidney dysfunction, organic heart disease, rheumatoid arthritis, systemic lupus erythematosus, polycystic kidney disease, psychiatric disorders, HIV/tuberculosis/HCV and other chronic diseases; ? Having a history of using glucocorticoids, estrogen, progesterone or insulin within 3 months prior to enrollment; ? Being unable to cooperate with follow-up due to personal reasons; ? Being in gestation or preparing for pregnancy; ?In addition, it also includes: 1) patients who are participating in other clinical trials within one month before the trial; 2) Researchers believe that other reasons are not suitable for clinical trial participants
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| weight;body mass index;sex hormone; | — |
Secondary
| Measure | Time frame |
|---|---|
| glycated hemoglobin A 1c (HbA1c);triglyceride(TG);total cholesterol(TC);high density lipoprotein cholesterol(HDL-C);Apolipoprotein B (apo B);Oral Glucose Tolerance Test (OGTT);Oral Glucose Insulin Release Test(OGIRT); | — |
Countries
China
Contacts
Public ContactDongfang Liu
The Second Affiliated Hospital of Chongqing Medical University
Outcome results
None listed