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Study on frailty-symptom interaction mechanisms and time point matching intervention strategies during postoperative adjuvant chemotherapy in elderly patients with colorectal neoplasms

Study on frailty-symptom interaction mechanisms and time point matching intervention strategies during postoperative adjuvant chemotherapy in elderly patients with colorectal neoplasms

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400090906
Enrollment
Unknown
Registered
2024-10-15
Start date
2026-06-01
Completion date
Unknown
Last updated
2024-10-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Neoplasms

Interventions

Intervention group:On the basis of conventional treatment in the control group, time point matching intervention will be implemented according to the interaction mechanism between frailty and symptoms
Control group:Routine care combined with continuous nursing.

Sponsors

Shanghai Tenth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: ?Patients after radical surgery for colorectal neoplasms; ?Age = 65 years old, regardless of gender; ?Patients receiving postoperative adjuvant chemotherapy; ?Basic self-care skills, KPS = 60 points; ?Normal communication skills; ?Be informed of the research content and methods, and sign the informed consent form.

Exclusion criteria

Exclusion criteria: ?Patients with severe cardiac, cerebral, renal and other organ dysfunction; ?Participating in other clinical trials that may affect the results of this study; ?History of other malignant tumours; ?Expected survival time <6 months; ?recurrence or metastasis of the tumor; ?Dementia.

Design outcomes

Primary

MeasureTime frame
Frailty score;Severity of Symptoms;

Secondary

MeasureTime frame
Quality of life level;Rehabilitation management quality indicators;Chemotherapy completion rate;

Countries

China

Contacts

Public ContactQian Wu

Shanghai Tenth People's Hospital

qian_wu2010@163.com+86 139 1621 9036

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026