None
Conditions
Interventions
Experimental group:PDA closure via femoral venipuncture without angiography under ultrasound
guidance
Control group:PDA closure via femoral arteriovenous puncture under traditional descending aortography
Sponsors
Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College
Tibet Autonomous Region People's Hospital
Eligibility
Sex/Gender
All
Age
3 Years to 63 Years
Inclusion criteria
Inclusion criteria: (1) Preoperative physical examination reveals Grade II to III systolic murmurs heard at the left sternal border in the 2nd to 3rd intercostal spaces; (2) Transthoracic echocardiography (TTE) indicates typical funnel-shaped patent ductus arteriosus (PDA) with clear visualization of PDA morphology and size under good acoustic window conditions.
Exclusion criteria
Exclusion criteria: (1) Patients with infective endocarditis or right-to-left shunt due to pulmonary hypertension; (2) Patients in combination with other cardiac defects requiring open surgery; (3) Patients with PDA-dependent heart defects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24h complete plugging rate;success rate of operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| fluoroscopy time;surgical radiation dose;intraoperative contrast dose;time of surgery;length of hospitalization;incidence of vascular complicatios;duration of bed confinement;preoperative and postoperative creatinine;preoperative and postoperative uric acid nitrogen; | — |
Countries
China
Contacts
Public ContactHu Haibo
Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College
Outcome results
None listed