Adolescent depression
Conditions
Interventions
intervention group:Based on basic medication and psychiatric routine care the patients were given transcranial alternating current stimulation (tACS), When the patient could not tolerate it, the inte
control subjects:Transcranial electrical pseudo-stimulation was given on the basis of the basic treatment, in order to make the subject produce the same subjective sensation as the real stimulation wi
Sponsors
Zhongda Hospital, Affiliated to Southeast University
Eligibility
Sex/Gender
All
Age
12 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. Patients with depressive disorders who meet the diagnostic criteria of the Diagnostic and Statistical Manual of Mental Disorders (5th Edition) (DSM-5) in the United States; 2. Age 12~18 years old (inclusive), male and female gender are not limited; 3. 24-item Hamilton Depression Rating Scale (24-item Hamilton Depression Rating Scale, HAMD-24) score = 20 points; 4. Obtain informed consent from the patient and legal guardian; 5. No obvious intellectual disability, able to understand the questionnaire assessment related topics; 6. Normal or corrected vision 7. Use of Zoloft as a base drug
Exclusion criteria
Exclusion criteria: 1. Present or past presence of the following disorders: schizophrenia, delusional disorder, bipolar disorder, dementia, or other severe cognitive impairment, mental disorder due to a physical illness or substance abuse; 2. History of traumatic brain injury or other known organic lesions of the central nervous system; 3. A history of modified electro-convulsive therapy (MECT) within 6 months prior to assessment; 4. Depressive episodes accompanied by psychotic symptoms; 5. The presence of pacemakers, metallic implants (e.g., stents) in the body. 6. Acute suicide risk as demonstrated by a score of 3-4 on the HDRS-17 suicide program 7. Concurrent participation in other clinical trials 8. Change in medication use within 2 weeks 9. Use of benzodiazepines
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Depression Rating Scale;Hamilton Anxiety Rating Scale;Positive and Negative Suicide Ideation;Adolescent Self-Rating Life Events Checklist;Childhood Trauma Questionnaire, 28 item Short Form;dimensional anhedonia ratingscale;Toronto Alexithymia Scale;Family Care Index Scale;Functional Assessment of Self-Mutilation;EEGERP tasks; | — |
Countries
China
Contacts
Public ContactHaixai Feng
Zhongda Hospital, Affiliated Southeast University
Outcome results
None listed