Coronary heart disease
Conditions
Interventions
CT-FFR Steering Group:The study intends to include patients visiting the emergency department of participating units due to suspected ACS, excluding STEMI and other patients with indications of emerge
Standard treatment group:CT-FFR examination was not performed in the standard treatment group
Sponsors
The Sixth Medical Center of PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Clinically suspected NSTEACS, meeting at least one of the following high-risk criteria: (1) Electrocardiographic changes suggest new ischemia (new ST-T segment depression, 2 consecutive lead levels or 0.05mV decrease, and/or 2 lead T wave inversion > 0.01mV with high R wave or R/S ratio > 1); (2) The level of circulating troponin increased. 2, age =18 years old; 3. Patients and their families can understand the purpose of this study and sign informed consent.
Exclusion criteria
Exclusion criteria: General exclusion criteria: 1. Patients with a history of coronary artery bypass grafting, coronary stent implantation, occluder implantation, artificial valve replacement and permanent pacemaker implantation; 2, NYHA grade III to IV heart failure patients; 3. Patients with any factors affecting coronary CTA and angiographic image quality (such as severe arrhythmia); 4, pregnant patients; 5. Patients with indications of emergency ICA; 6. Patients with known intolerance to platelet inhibitors, heparin or X-ray contrast agents that cannot be remedied by medical means; CT-FFR exclusion criteria: 1. Patients with serum creatinine > 150µmol/L or GFR < 45 ml/kg/1.73m2; 2. Patients with known atrial fibrillation; 3. Patients with insufficient image quality to support analysis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of patients without obstructive coronary artery disease receiving ICA and those with obstructive coronary artery disease who received no intervention within 90 days; | — |
Secondary
| Measure | Time frame |
|---|---|
| Major cardiovascular adverse events;Decision time;Quality of life score;Angina symptoms;Time from puncture to balloon dilation in patients receiving ICA;Total medical expenditures at 1 year follow-up; | — |
Countries
China
Contacts
Public ContactYang Junjie
The Sixth Medical Center of PLA General Hospital
Outcome results
None listed