Facial Aging
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Females aged 25-50 years (inclusive of 25 and 50 years). 2.Mild to moderate facial aging, lack of elasticity, rough and dull skin (refer to the skin aging scale). 3.Facial crow's feet, under-eye wrinkles, forehead lines, nasolabial folds, and glabellar lines. 4.No cosmetic procedures such as laser chemical peels within the past 3 months before the test. 5.Voluntarily participate in the test and sign the informed consent, maintaining original lifestyle during the test. 6.Able to comply with and participate in follow-up visits, adhere to daily photo check-ins, and promptly report any changes in health status or adverse reactions during the test. 7.Avoid excessive sun exposure during the test period
Exclusion criteria
Exclusion criteria: 1.Women who are pregnant, lactating, or intending to conceive. 2.Individuals with photosensitivity/scar constitution. 3.Patients currently participating in other clinical trials. 4.Patients with wounds, epidermal rupture, herpes/folliculitis at the test site. 5.Individuals whose test sites have scars, pigmentation, atrophy, port wine stains, or 6.other imperfections that affect the judgment of test results. 7.Patients with diabetes, tumors, asthma, autoimmune diseases, or other severe organic or mental diseases. Individuals who have taken oral antihistamines within the past week, applied any anti-inflammatory drugs to the test site within the past two months, or used retinoids, alpha hydroxy acids, salicylic acid, hydroquinone, etc., within the past three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Facial spots, texture, pores, and wrinkles;Facial stratum corneum hydration, sebum content, skin elasticity, firmness, glossiness;Facial dermal thickness and density; | — |
Secondary
| Measure | Time frame |
|---|---|
| Participant satisfaction score; | — |
Countries
China
Contacts
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine