Tumor
Conditions
Interventions
A:Dynamic PET/CT scan to assess the biodistribution, pharmacokinetics and dosimetry of [18F]AlF-ETN in human
B:Using PET/CT to evaluate tumor uptake of [18F]AlF-ETN in patients with malignant solid tumors
Sponsors
Cancer Hospital Chinese Academy of Medical Sciences Union Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: ? Healthy Volunteers: Aged between 18 and 80 years old, capable of cooperating independently to complete the examinations; having full comprehension and voluntarily participating in this experiment, and signing the informed consent form. ? Malignant Tumor Patients: Patients with confirmed malignant tumors such as pancreatic cancer, gastric cancer, colorectal cancer, squamous cell carcinoma of the head and neck, cervical cancer, ovarian cancer, endometrial cancer, breast cancer, esophageal cancer, lung cancer, etc., who have not received tumor-related treatments yet; aged between 18 and 80 years old, capable of cooperating independently to complete the examinations; having full comprehension and voluntarily participating in this experiment, and signing the informed consent form.
Exclusion criteria
Exclusion criteria: Severe abnormal of liver function, kidney function or blood routine test; Pre-pregnancy, pregnant or lactating women; Unable to lie flat for half an hour; Suffering from claustrophobia or other mental illness; Unable to understand the examination process or unable to cooperate; Other circumstances that the investigator considers inappropriate for trial participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| safety;Standard intake value; | — |
Countries
China
Contacts
Public ContactXuejuan Wang
Cancer Hospital Chinese Academy of Medical Sciences
Outcome results
None listed