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Clinical effect of Watermelon Frost Oral Spray on dry mouth and sore throat after thoracoscopic lobectomy of lungs:a clinical randomized controlled study

Clinical effect of Watermelon Frost Oral Spray on dry mouth and sore throat after thoracoscopic lobectomy of lungs:a clinical randomized controlled study

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400090836
Enrollment
Unknown
Registered
2024-10-14
Start date
2024-10-17
Completion date
Unknown
Last updated
2024-10-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-operative Sore Throat

Interventions

( Group WFS): Patients into the operating room, routine ECG monitoring, oxygen inhalation, open peripheral venous access, Group WFS group was given watermelon frost buccal spray, the specific practice
( Group C):Patients into the operating room, routine ECG monitoring, oxygen inhalation, open peripheral venous access, Group C group was given sterilized injection water spray, the specific practice

Sponsors

The First Afliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1)Single lung ventilation with double-lumen bronchial tube during thoracoscopic lobectomy of lungs under general anesthesia; (2) ASA (American Society of Anesthesiologists) preanesthetic condition grade I ~ III, aged 18 ~ 65 years, height 150 ~ 184 cm, body weight 47 ~ 78 kg, BMI < 30 kg / m2; (3) Normal communication and voluntary acceptance of the experiment.

Exclusion criteria

Exclusion criteria: (1) Allergic to watermelon frost spray; Serious respiratory and circulatory diseases, such as serious coronary heart disease, chronic obstructive pulmonary disease, and a long history of smoking; Endocrine system disorders, such as pituitary adenomas, serious diabetes mellitus, hypercortisolism, pheochromocytoma, etc. A history of disease, such as schizophrenia, depression; (5) History of chronic pain, long-term use of pain-relieving drugs, alcohol abuse, opioid dependence, and failure to perform visual analogue scale (VAS) correctly; (6) bleeding disease or abnormal coagulation function; (7) history of chronic pharyngitis; History of reflux esophagitis; (8) Previous tonsil or vocal cord surgery; (9) long-term use of glucocorticoid during perioperative period; (10) Patients with difficult airway and > 2 intubations; (11) The operation time exceeds 4 hours; (12) Serious adverse events occurred during the operation; (13) postoperative re-emergency operation; (14) Those who were transferred to ICU after surgery.

Design outcomes

Primary

MeasureTime frame
Hoarseness is graded as follows: Level 1 is the micro tone becomes low and coarse; Grade 2 moderate tone becomes lower and thicker; Level 3: Can only whisper or lose voice;

Secondary

MeasureTime frame
Sore throat;dry thirst;Nausea and vomiting;Odynphagia;

Countries

China

Contacts

Public Contactxuanxuan wang

The First Afliated Hospital of Anhui Medical University

584789335@qq.com+86 137 0560 3342

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026