overweight
Conditions
Interventions
Lunch fasting group:Fasting during lunch and limiting the total calorie intake for the day
Calorie Restriction:Reduce energy intake by 25% in a day
Sponsors
The First Affiliated Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1) Age range from 18 to 45 years old; 2) 24 kg/m^2 = Body Mass Index, BMI)<35 kg/m^2; 3) The weight should remain stable for the first 3 months before the start of the experiment.
Exclusion criteria
Exclusion criteria: 1) Metabolic diseases such as diabetes and hyperthyroidism; 2) Abnormal liver and kidney function; ( ALT or AST is more than 3 × ULN, eGFR is less than 30 ml/min/1.73 m2) 3) Malignant tumors; 4) Taking medications that affect weight loss outcomes, such as antidepressants, thyroid hormones, etc; 6) Eating disorders or vegetarianism; 7) Night shift, insomnia, smoking and alcohol abuse; 9) Pregnancy, planned pregnancy, lactation, or menstrual disorders;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| weight; | — |
Secondary
| Measure | Time frame |
|---|---|
| body composition;Basal metabolic rate;blood sugar;blood fat;liver function; | — |
Countries
China
Contacts
Public ContactYun Zhang
The First Affiliated Hospital of Zhejiang University School of Medicine
Outcome results
None listed