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A multicenter clinical study of normal myocardial strain and Z-Score in healthy children in Anhui area

A multi-center registration study of normal myocardial strain and Z-Score in healthy children in Anhui area

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400090805
Enrollment
Unknown
Registered
2024-10-14
Start date
2024-11-01
Completion date
Unknown
Last updated
2024-10-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

none

Interventions

Infant group, early childhood group, school age group, pre-school age group, adolescent group:None

Sponsors

The First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
28 Days to 18 Years

Inclusion criteria

Inclusion criteria: ? Han Nationality ?28 days = age < 18 years old ? Normal blood pressure (refer to pediatrics guidelines) ?Experienced doctors judge that the heart structure and function are normal; Patients < 1 year of age with patent foramen ovale or mild pulmonary artery stenosis (maximum instantaneous gradient < 15 MMHG) were included in the normal group ? Sign informed consent

Exclusion criteria

Exclusion criteria: ? All other abnormalities of the heart, including patent ductus arteriosus of any size; (2) Echocardiographic studies under sedation and anesthesia; ? The following patients: Non-cardiac comorbidities with potential cardiovascular effects (e.g., muscular dystrophy, kidney disease, storage disease, lung disease or severe anaemia); Hypertension (systolic or diastolic) >95% percentile or taking prescribed blood pressure medications; Cardiomyopathy of a first-degree relative (parent, child or sibling); Weight, heart rate, or any echocardiographic measurement Z-score 2.5; The image quality of the speckle tracking analysis was insufficient (i.e., more than two segments or all endocardial boundaries were not visible in the qualitative assessment); Children who cannot cooperate to complete an echocardiogram.

Design outcomes

Primary

MeasureTime frame
Left atrial strain;Right atrial strain;Left ventricular strain;Right ventricular strain;Left Ventricular Ejection Fraction ;

Secondary

MeasureTime frame
Left Atrial Diameter;Left ventricular end diastolic diameter;Right atrium left and right diameter;Right atrium upper and lower diameter;Transverse diameter of right ventricle base;Left ventricle end-diastolic volume;Left ventricular end-systolic volume;Tricuspid annular plane systolic excursion ;Mitral annular plane systolic excursion ;

Countries

China

Contacts

Public ContactYang Dongmei

The First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital)

Dmymail627@126.com+86 139 5696 0715

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026