none
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? Han Nationality ?28 days = age < 18 years old ? Normal blood pressure (refer to pediatrics guidelines) ?Experienced doctors judge that the heart structure and function are normal; Patients < 1 year of age with patent foramen ovale or mild pulmonary artery stenosis (maximum instantaneous gradient < 15 MMHG) were included in the normal group ? Sign informed consent
Exclusion criteria
Exclusion criteria: ? All other abnormalities of the heart, including patent ductus arteriosus of any size; (2) Echocardiographic studies under sedation and anesthesia; ? The following patients: Non-cardiac comorbidities with potential cardiovascular effects (e.g., muscular dystrophy, kidney disease, storage disease, lung disease or severe anaemia); Hypertension (systolic or diastolic) >95% percentile or taking prescribed blood pressure medications; Cardiomyopathy of a first-degree relative (parent, child or sibling); Weight, heart rate, or any echocardiographic measurement Z-score 2.5; The image quality of the speckle tracking analysis was insufficient (i.e., more than two segments or all endocardial boundaries were not visible in the qualitative assessment); Children who cannot cooperate to complete an echocardiogram.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Left atrial strain;Right atrial strain;Left ventricular strain;Right ventricular strain;Left Ventricular Ejection Fraction ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Left Atrial Diameter;Left ventricular end diastolic diameter;Right atrium left and right diameter;Right atrium upper and lower diameter;Transverse diameter of right ventricle base;Left ventricle end-diastolic volume;Left ventricular end-systolic volume;Tricuspid annular plane systolic excursion ;Mitral annular plane systolic excursion ; | — |
Countries
China
Contacts
The First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital)