Gallstones, Cholecystitis, Gallbladder polyps, Cholelithiasis
Conditions
Interventions
Bupivacaine liposome injection group (Group BL):Bupivacaine liposome injection locally infiltrated the anesthetic wound
Ropivacaine hydrochloride injection group (Group RP):Ropivacaine hydrochloride injection 15ml local infiltration anesthesia wound
Sponsors
Affiliated Hospital of Guizhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Patients aged 18-65 years old, regardless of gender; (2) BMI of 18 ~ 30kg/m2; (3) ASA grade I and II; (4) Patients who plan to undergo laparoscopic cholecystectomy under general anesthesia; (5) The subjects voluntarily participate and sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with contraindications to local anesthesia; (2) Allergic to or contraindicated with the drugs used in the study (such as opioids, muscle relaxants, etc.) or their ingredients; (3) Patients with craniocerebral injury, cerebrovascular accident history and central nervous system diseases; (4) long-term use of psychotropic drugs, narcotic analgesics, sedative hypnotics or non-steroidal anti-inflammatory drugs patients; (5) Patients who are judged to have difficult airway; (6) Participants who have participated in any clinical trial as a subject within 3 months before enrollment; (7) Other conditions deemed unsuitable for inclusion by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of Recovery-15 (QoR-15) score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual analogue scale-Pain score;Incidence of postoperative vomiting;postoperative consumption of opioids;Length of stay;Incidence of postoperative complications;adverse reactions ;Group-time interaction effects on the QoR-15 and its sub-scores were analyzed using a linear mixed model; | — |
Countries
China
Contacts
Public Contacthubailong
Affiliated Hospital of Guizhou Medical University
Outcome results
None listed