Chronic ulcer
Conditions
Interventions
Control Group:Debridement and platelet-rich plasma gel therapy
Test group:Debridement and platelet-rich plasma gel patch therapy
Sponsors
Sir Run Run Shaw Hospital, College of Medicine Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) 18 -75 years old; 2) Patients with chronic wounds who need debridement and repair; 3) The wound duration is more than 4 weeks; 4) Voluntary participation in this study and signing of informed consent;
Exclusion criteria
Exclusion criteria: 1) Patients with severe thrombocytopenia and septicemia; 2) Patients who are allergic to rubber components; 3) Patients who have been injected with glucocorticoids within one month or received systemic corticosteroid treatment within two weeks; 4) Patients with malignant tumor; 5) Hemoglobin < 100 g/L and platelet count < 100× 109/L; 6) Mental illness, cognitive impairment, critically ill patients, minors and pregnant women; 7) Those who have participated in or are participating in clinical trials of drugs within 3 months, or participated in or are participating in clinical trials of other medical devices within 30 days; 8) Other circumstances that the researcher considers inappropriate to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Platelet concentration; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gel tensile strength;Growth factor concentration;Bacterial status of wound surface 3 days after operation;Postoperative wound condition; | — |
Countries
China
Contacts
Public ContactQiang Wang
Sir Run Run Shaw Hospital, College of Medicine Zhejiang University
Outcome results
None listed