Coronary microvascular disease, CMD
Conditions
Interventions
Gold Standard:Index of Microcirculatory Resistance,IMR. People with IMR=25 will be diagnosed as CMD.
Index test:IMRct was the first parameter to be named for the original computational model constructed by our research group and the team from Sun Yat-sen University. The definiton of IMRct is a estima
Sponsors
The First Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >=18 years old; 2. For suspected coronary atherosclerotic heart disease, CCTA was performed within 1 month before admission. Completed intracavitary functional examination (FFR, IMR, CFR) during the hospitalization; 3. Be able to understand the purpose of this study and sign the informed consent; 4. Be able to comply with all research requirements; 5. CCTA image data is required by standardized image acquisition and reconstruction Settings, and the image quality is good, meeting the analysis requirments; 6. The stenosis of subepicardial great vessel is 30% to 90% or coronary contrast agent retention or TIMI is grade 2. 7. The data of coronary angiography and intracavitary functional indexes (FFR, IMR, CFR) were completed.
Exclusion criteria
Exclusion criteria: 1. Acute myocardial infarction; 2. Stenosis of left main coronary artery >=50%; 3. Previous PCI or CABG; 4. Chronic complete occlusive disease of coronary artery; 5. Hypertrophic cardiomyopathy (both obstructive and non-obstructive); 6. Severe obstructive heart disease, such as moderate to severe aortic stenosis, mitral stenosis, etc; 7.Tako Tsubo Syndrome (TTS); 8. Arrhythmias affect image analysis, such as atrial fibrillation and frequent ventricular premature; 9. Life expectancy 400; 12. Myocardial bridge compression of more than 70%; 13. Other situations that are not suitable for inclusion in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity; | — |
Countries
China
Contacts
Public ContactZhihui Zhang
The First Affiliated Hospital of Army Medical University
Outcome results
None listed