Effects of various dietary fiber intervention strategies on gut microbiota and mental health in healthy adults

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400090711

Enrollment

Unknown

Registered

2024-10-12

Start date

2024-10-18

Completion date

Unknown

Last updated

2025-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

MCC Group:Participants in the MCC intervention group will ingest a half dose (25g/day for women and 35g/day for men) of microcrystalline cellulose powder daily before breakfast and before dinner.

AX Group:Participants in the AX intervention group will ingest a half dose (25g/day for women and 35g/day for men) of arabinogalactan powder daily before breakfast and before dinner.

MAX Group:Participants in the MAX intervention group will consume half a dose (25g/day for women and 35g/day for men) of microcrystalline cellulose powder daily before breakfast

and half a dose (25g/day for women and 35g/day for men) of arabinoxylan powder before dinner.

Eligibility

Sex/Gender

All

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: 1.Age: 18-55 years old (adults), gender is not limited; 2.Healthy (no clinically diagnosed mental illness or physical illness that would affect mental health at the time of enrolment); 3.Not pregnant; 4.If you are already using probiotic or prebiotic products, stop using them for at least 4 weeks; 5.Understand the experimental procedures and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Unwillingness to accept informed consent; 2. Pregnant women; 3. Patients with diseases that may affect the project or are not suitable for clinical research; 4. Patients suffering from mental disorders or cognitive disorders; 5. Patients who have participated in other clinical trials within 4 weeks prior to the start of this project.

Design outcomes

Primary

Measure	Time frame
Mental Health Questionnaire;Gut Microbiota;Blood metabolomics;	—

Secondary

Measure	Time frame
Basic information on demography;Questionnaires on exercise, satiety, gastrointestinal symptoms, faecal pattern and frequency of bowel movements.;Fitbit (sleep );Body composition analysis;Salivary cortisol;Immunological and routine biochemical ;	—

Countries

China

Contacts

Public ContactChenxi Cai

Xiamen University

chenxicai@xmu.edu.cn+86 592 218 6358

Outcome results