Skip to content

Prospective randomized controlled study on whether TACE combined with PVE can reduce the recurrence rate of large liver cancer after surgery

Prospective randomized controlled study on whether TACE combined with PVE can reduce the recurrence rate of large liver cancer after surgery

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400090666
Enrollment
Unknown
Registered
2024-10-11
Start date
2024-04-25
Completion date
Unknown
Last updated
2024-10-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular carcinoma

Interventions

Experimental group:TACE+PVE+Hepatectomy

Sponsors

the Third Affiliated Hospital, Naval Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 18 and 70 years old; 2. Clinical diagnosis of hepatocellular carcinoma (clinical diagnosis criteria for hepatocellular carcinoma: meet the 2024 Guidelines for Primary liver Cancer Diagnosis and Treatment or 2022 Barcelona stage) : a) Stage Ib or IIa of CNLC or stage A or B1 of BCLC with a single tumor diameter greater than 5cm or = 100*10^9/L, HBV-DNA 10^3; 10. Sign informed consent;

Exclusion criteria

Exclusion criteria: 1. Tumor types other than the inclusion criteria; 2. Have a history of other tumors; 3. Serious concomitant diseases (cardiovascular and cerebrovascular diseases, etc.); 4. Cirrhosis with esophageal varicose veins; 5. Platelet < 100*10^9/L;

Design outcomes

Primary

MeasureTime frame
median progression free survival, mPFS;

Secondary

MeasureTime frame
median overall survival, mOS;MVI positive rate;Tumor necrosis rate;Complication rate;

Countries

China

Contacts

Public ContactZHOU Weiping, NI Junsheng

Eastern Hepatobiliary Surgery Hospital, the Third Affiliated Hospital of Naval Medical University

nijs77@me.com+86 134 8275 9538

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026