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Analysis of the pH value of synovial fluid in different joint diseases

Analysis of the pH value of synovial fluid in different joint diseases

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400090636
Enrollment
Unknown
Registered
2024-10-10
Start date
2024-10-14
Completion date
Unknown
Last updated
2024-10-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Osteoarthritis,Rheumatoid Arthritis,Kashin-Beck Disease,Developmental Dislocation of the Hip,Avascular Necrosis of the Femoral Head,Ankylosing Spondylitis, Periprosthetic joint infection, Aseptic failure after total joint arthroplasty

Interventions

Gold Standard:The 2018 Musculoskeletal Infection Society (MSIS) diagnostic criteria for periprosthetic joint infection
Index test:Synovial fluid pH value

Sponsors

the First Affliated Hospital of Xinjiang Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. The diagnosis of patients in the experimental group should meet the 2018MSIS PJI criteria; 2. Patients in control group 1 should be diagnosed as aseptic loosening; 3. Patients in control group 2 underwent primary hip and knee arthroplasty due to osteoarthritis and rheumatoid arthritis.

Exclusion criteria

Exclusion criteria: 1. The primary disease of primary arthroplasty was infectious; 2. Patients with a history of metastatic disease (cancer); 3. Patients with drug use history.

Design outcomes

Primary

MeasureTime frame
Synovial fluid pH value;Receiver OperatingCharacteristic, ROC;Area Under Curve, AUC;

Secondary

MeasureTime frame
erythrocyte sedimentation rate;C-reactive protein;Synovial fluid leukocyte counts;Synovial fluid polymorphonuclear leukocytes;Results of synovial fluid culture;

Countries

China

Contacts

Public ContactLi Cao

The First Affliated Hospital of Xinjiang Medical University

xjbone@163.com+86 139 0991 5960

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026