Henoch Schonlein purpura
Conditions
Interventions
Control group:Injection of methylprednisolone sodium succinate and Vitamin C injection and Omeprazole Injection
Treatment group:Injection of methylprednisolone sodium succinate and Vitamin C injection and Omeprazole Injection and Self-made Chinese herbal remedy
Sponsors
Beijing Children's Hospital
Eligibility
Sex/Gender
All
Age
5 Years to 18 Years
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria for pediatric HSP, accompanied by gastrointestinal symptoms such as abdominal pain, vomiting, etc., and meet one of the following three criteria: visible gastrointestinal bleeding such as hematemesis, bloody stools, etc.; positive fecal occult blood test; intestinal wall swelling shown on abdominal ultrasound; (2) The diagnosis conforms to the internal damp-heat syndrome; (3) Ages 5-18; (4) Children entering the group must have informed consent from their legal guardians.
Exclusion criteria
Exclusion criteria: (1) People with severe heart, brain, liver, kidney, lung, and hematopoietic system diseases at the time of selection; (2) Those participating in other clinical trials of drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Symptom and Sign Scoring; | — |
Secondary
| Measure | Time frame |
|---|---|
| Eruption subsides over time;Relief time for digestive symptoms;Plasma DAO;D-lactic acid;Endotoxin;Th17/Treg; | — |
Countries
China
Contacts
Public ContactZhao Qian
Beijing Children's Hospital
Outcome results
None listed