Oral polymyxin for decolonization of Carbapenem-resistant gram-negative organism (CRO) in intestinal: A Prospective, Multicenter, Randomized Controlled Study

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400090612

Enrollment

Unknown

Registered

2024-10-10

Start date

2024-10-14

Completion date

Unknown

Last updated

2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intestinal colonization of carbapenem-resistant organism

Interventions

experimental group:oral polymyxin tablets

control group:None

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1) age = 18 years old 2) intestinal colonization of CRO is confirmed by rectal swab or fecal microbial culture 3) voluntarily participate in this study and sign the informed consent form; if the subject is unable to understand or sign the informed consent form, their legal representative will act on their behalf in the informed process and agree to their participation in this study

Exclusion criteria

Exclusion criteria: 1)The CRO strains colonized are resistant to polymyxins 2)Women who are pregnant or breastfeeding.

Design outcomes

Primary

Measure	Time frame
the clearance of CRO colonized in intestinal;	—

Secondary

Measure	Time frame
the MIC of CRO colonized in the instestine;	—

Countries

CHINA

Contacts

Public ContactYu Yunsong

Zhejiang Provincial People’s Hospital

yvys119@163.com+86 138 0579 0432

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 17, 2026