sepsis
Conditions
Interventions
Sponsors
Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: For patients with sepsis and other severe infections, upon admission or during hospitalization, if they meet conditions ? and ?, with or without ? and ?: ? Body temperature >38°C or 90 beats per minute or hypotension (systolic blood pressure 40 mmHg from baseline). ? Rapid breathing (>20 breaths per minute) or hyperventilation (PaCO2 <32 mmHg).
Exclusion criteria
Exclusion criteria: 1) Coexisting malignancies, including hematological tumors and solid tumors; 2) Rheumatic connective tissue diseases; 3) Congenital coagulation disorders: Hemophilia A, B, C; Von Willebrand disease; Deficiencies of coagulation factors (congenital deficiencies of factors ?, ?, ?, ?, ?, ?, ?, ??, and prekallikrein); 4) Concurrent other underlying diseases, currently using anticoagulant drugs such as heparin, warfarin, oral novel anticoagulants, antiplatelet agents, etc.; 5) Received major surgery within the past 2 weeks; 6) The patient or authorized representative is unable to sign or refuses to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical features of sepsis and other severe infection-related coagulopathy ; | — |
Countries
China
Contacts
Public ContactQin Ning
Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed