None
Conditions
Interventions
C group:Intravenous induction is performed with ciprofol in combination with sufentanil
P group:Intravenous induction is performed with propofol in combination with sufentanil
Sponsors
The First People's Hospital of Jingzhou
Eligibility
Sex/Gender
All
Age
60 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.The clinical data of patients are complete 2.Patients aged 60~75 who are scheduled to undergo elective surgery under general anesthesia 3.ASA Grades II-III 4.18=BMI<30kg/m2 5.Modified Mallampati Classification I-II
Exclusion criteria
Exclusion criteria: 1.Patient has a history of previous drug allergy to general anesthesia 2.The patient has a difficult airway 3.The patient had severe dysfunction of important organs such as heart, lungs, and brain 4.The patient has a non-invasive systolic blood pressure = 160 mmHg or = 90 mmHg and a non-invasive diastolic blood pressure = 100 mmHg after admission to the operating room. 5.Patient has an inferior vena cava collapse index (IVC-CI) of > 50% and an end-inspiratory inferior vena cava width (IVCMAX) of = 2.1 cm (volume too low) or IVC-CI 2.1 cm (volume is too high) before the start of induction, 6.Patients with a positive Allen test on the left hand
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Invasive arterial blood pressure;Heart beat;Incidence of hypotension;Incidence of bradycardia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Narcotrend Index;injection pain; | — |
Countries
China
Contacts
Public ContactRui Xia
The First People's Hospital of Jingzhou
Outcome results
None listed