Pre-MRI Sedation
Conditions
Interventions
experimental group:Subjects were sedated using dexmedetomidine nasal spray
control group:Subjects were sedated by nasal drops of dexmedetomidine hydrochloride injection
Sponsors
Children's Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
1 Years to 2 Years
Inclusion criteria
Inclusion criteria: (1) ASA I-II level; (2) Age 1-2 years old; (3) Children weighing 10-15kg (4) requiring sedation before MRI examination
Exclusion criteria
Exclusion criteria: (1) ASAIII level and above; (2) nasal mucosa injury in children; (3) severe upper respiratory tract infection; (4) dysfunction of liver and kidney; (5) History of sedative drug allergy; (6) Experienced general anesthesia within 2 weeks; (7) Use of sedative hypnotics (including benzodiazepines such as diazepam and barbiturates such as phenobarbital, etc.) within 1 week; (8) mental system diseases and cognitive dysfunction; (9) Arrhythmia, especially chronic arrhythmia; (10) Severe obesity (weight =50% above the standard body weight); (11) follow-up missing; (12) Refuse to participate in this study; (13) Other conditions that the investigator determines are not suitable for participation in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation success rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sedation time; adverse event;Sedation satisfaction rate;Success rate of rescue sedation;vital signs;recovery time; | — |
Countries
China
Contacts
Public ContactJinjin Huang
Children's Hospital, Zhejiang University, School of Medicine
Outcome results
None listed