Lung cancer
Conditions
Interventions
Index test:Analysis results of serum proteomics testing
Sponsors
Zhejiang cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Common inclusion criteria (both groups of people must meet all of the following criteria): (1) Age = 18 years old; (2) Through chest CT examination, pulmonary nodules with a diameter of = 30mm were found; (3) Having complete clinical information; (4) Understand the research and have the willingness to sign an informed consent form; Individual inclusion criteria: Malignant pulmonary nodule group: Imaging suggests that the nodule may be highly malignant, and subsequent surgery or biopsy pathology confirms it as primary lung cancer. Benign pulmonary nodules group: those who are considered to have a high possibility of benign conditions based on imaging examinations and clinical manifestations, and therefore adopt conservative treatment strategies; Or if the imaging suggests malignancy, but it is confirmed by pathology to be a benign nodule.
Exclusion criteria
Exclusion criteria: (1) Individuals with a history of primary lung cancer or other malignant tumors (including multiple myeloma, monoclonal immunoglobulin disease, and other cancers that cause excessive serum immunoglobulin levels); Received anti-tumor treatment before enrollment, including surgical treatment, radiotherapy, chemotherapy, etc; (2) Individuals who have undergone lung resection or percutaneous lung biopsy prior to enrollment; (3) Blood transfusion recipients within 30 days prior to enrollment; (4) Pregnant or lactating women; (5) Other researchers believe that it is not suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proteomics;Accuracy;Sensitivity;Specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive predicative value;Negative predictive value; | — |
Countries
China
Contacts
Public ContactJian Zeng
Zhejiang cancer hospital
Outcome results
None listed