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A clinical study investigating the diagnosis of normal pressure hydrocephalus based on cerebrospinal fluid dynamics

A clinical study investigating the diagnosis of normal pressure hydrocephalus based on cerebrospinal fluid dynamics

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400090552
Enrollment
Unknown
Registered
2024-10-08
Start date
2024-08-30
Completion date
Unknown
Last updated
2024-10-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Normal Pressure Hydrocephalus

Interventions

Gold Standard:Guidelines for management of idiopathic normal pressure hydrocephalus (Third Edition): Endorsed by the Japanese Society of Normal Pressure hydrocephalus
Index test:By conducting infusion experiments on patients, measuring a series of physiological parameters such as intracranial pressure during lumbar puncture, calculating the patients outflow resista

Sponsors

Tianjin Medical University General Hosipital,Tianjin University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
24 Years to 88 Years

Inclusion criteria

Inclusion criteria: Patients with ventricular dilation on CT or indications of DESH on MRI, as well as those with gait disorders, advanced cognitive impairment, or urinary disorders clinically present

Exclusion criteria

Exclusion criteria: There are contraindications for lumbar puncture

Design outcomes

Primary

MeasureTime frame
Area under the curve (AUC);Specificity;—

Secondary

MeasureTime frame
Sensitivity;—

Countries

China

Contacts

Public ContactXiuyun Liu, Huijie Yu, Kai Yu, Dong Ming

Tianjin University,Tianjin Medical University General Hosipital,Tianjin Medical University General Hosipital,Tianjin University

xiuyun_liu@tju.edu.cn+86 138 2059 4672

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026