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Study on the mechanism of the protection of retinal ganglion cells by the microbial community regulating the immune microenvironment in vivo

Study on the mechanism of the protection of retinal ganglion cells by the microbial community regulating the immune microenvironment in vivo

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400090540
Enrollment
Unknown
Registered
2024-10-08
Start date
2023-12-01
Completion date
Unknown
Last updated
2024-10-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Interventions

Patients with PSS group:none
Patients with cataract group:none
Intraocular lens implantation (ICL) group:none
Patients with glaucoma group:none

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) patients in the control group had corresponding surgical indications; (2) The patient was immunocompetent; (3) no autoimmune disease or chronic infection; (4) Patients with PSS can be followed up on time.

Exclusion criteria

Exclusion criteria: (1) Elderly patients (>80 years old) with poor basic conditions and many combined influencing factors were difficult to evaluate; (2) pregnant patients; (3) those who could not tolerate corneal confocal microscopy and other relevant examinations.

Design outcomes

Primary

MeasureTime frame
intraocular microbiota;gut microbiota;Metabolites in the blood;—

Secondary

MeasureTime frame
visual acuity;intraocular pressure;visual field;Nerve fiber layer thickness;—

Countries

China

Contacts

Public ContactChun Zhang

Peking University Third Hospital

zhangc1@yahoo.com+86 186 0103 1059

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026