Postoperative Pain
Conditions
Interventions
B-grouop:pre-incisional infiltration with bupivacaine liposome
C-group:pre-incisional infiltration with ropivacaine
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1)Age>18 years (2)Scheduled for elective acoustic neuroma surgery (3)American Society of Anesthesiologists(ASA) physical status I-III (4)Inform the relevant contents of this clinical trial and sign the informed consent
Exclusion criteria
Exclusion criteria: (1)Combination of severe cardiopulmonary, hepatic or renal dysfunction (2)History of mental illness or currently taking psychotropic medications (3)History of neurological diseases(cerebral infarction, transient ischemic attack, history of cerebral hemorrhage, Parkinson’s disease, mental retardation, craniocerebral injury) (4)Heart rate below 50bpm or prolonged QT interval on electrocardiogram (5)ECG indicates preexcitation syndrome, or confirm the history (6)Allergy to ropivacaine or bupivacaine liposome (7)Infection at the puncture site or systemic presence (8)History of craniotomy (9)Postoperative sedation for various reasons (10)Inability to understand visual analog scores(VAS) (11)Delayed extubation or admission to ICU with intubation for any reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative Pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative Pain;Changes in vital signs;intraoperative and postoperative analgesic use;incidence of postoperative nausea and vomiting ;endotracheal extubation time and length of stay in the recovery room;length of postoperative hospitalization and costs during hospitalization;Quality of postoperative recovery;postoperative complications; | — |
Countries
China
Contacts
Public ContactChen Feng
Department of Anesthesiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed